Paraskevi Heldin Selected Research

Hyaluronan Synthases

1/2019	Has2 natural antisense RNA and Hmga2 promote Has2 expression during TGFβ-induced EMT in breast cancer.
8/2014	TGFβ and matrix-regulated epithelial to mesenchymal transition.
12/2011	Hyaluronan synthase 2 (HAS2) promotes breast cancer cell invasion by suppression of tissue metalloproteinase inhibitor 1 (TIMP-1).
6/2007	Silencing of hyaluronan synthase 2 suppresses the malignant phenotype of invasive breast cancer cells.
7/2005	Antisense-mediated suppression of hyaluronan synthase 2 inhibits the tumorigenesis and progression of breast cancer.
4/2004	Renal hyaluronan accumulation and hyaluronan synthase expression after ischaemia-reperfusion injury in the rat.
11/2002	Expression of hyaluronan synthase 2 or hyaluronidase 1 differentially affect the growth rate of transplantable colon carcinoma cell tumors.

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Paraskevi Heldin Research Topics

Disease

18	Neoplasms (Cancer) 01/2022 - 11/2002
12	Breast Neoplasms (Breast Cancer) 01/2022 - 07/2005
7	Inflammation (Inflammations) 01/2020 - 11/2002
4	Carcinoma (Carcinomatosis) 01/2019 - 11/2002
3	Virus Diseases (Viral Diseases) 01/2020 - 01/2019
3	Carcinogenesis 11/2010 - 07/2005
2	Triple Negative Breast Neoplasms 01/2022 - 05/2020
2	Neoplasm Metastasis (Metastasis) 12/2011 - 07/2005
1	Pancreatitis 10/2021
1	Septic Shock (Toxic Shock Syndrome) 10/2021
1	Sepsis (Septicemia) 10/2021
1	Lung Neoplasms (Lung Cancer) 03/2021
1	Pathologic Processes 01/2020
1	Severe Dengue 10/2019
1	Fever (Fevers) 10/2019
1	Dengue (Dengue Fever) 10/2019
1	Infections 10/2019
1	Metabolic Diseases (Metabolic Disease) 01/2019
1	Prostatic Neoplasms (Prostate Cancer) 01/2019
1	Colonic Neoplasms (Colon Cancer) 05/2011
1	Cardiovascular Diseases (Cardiovascular Disease) 03/2011
1	Retinal Diseases 10/2007
1	Myxedema 01/2007
1	Thyroid Diseases (Thyroid Disease) 01/2007
1	Goiter 01/2007
1	Graves Ophthalmopathy 01/2007
1	Autoimmune Diseases (Autoimmune Disease) 01/2007
1	Reperfusion Injury 04/2004
1	Colorectal Neoplasms (Colorectal Cancer) 11/2002
1	Edema (Dropsy) 11/2002

Drug/Important Bio-Agent (IBA)

26	Hyaluronic Acid (Hyaluronan)IBA 01/2022 - 11/2002
7	GlycosaminoglycansIBA 05/2020 - 07/2005
7	Hyaluronan SynthasesIBA 01/2019 - 11/2002
4	EnzymesIBA 01/2019 - 06/2007
3	Hyaluronoglucosaminidase (Hyaluronidase)FDA Link 10/2021 - 11/2002
3	CytokinesIBA 01/2020 - 01/2014
2	Estrogen ReceptorsIBA 01/2022 - 01/2019
2	Phosphotransferases (Kinase)IBA 05/2020 - 01/2019
2	Proteins (Proteins, Gene)FDA Link 05/2020 - 10/2019
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020 - 01/2008
2	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2019 - 08/2014
2	Transforming Growth Factor beta1 (TGF beta 1)IBA 10/2007 - 06/2003
1	Progesterone Receptors (Progesterone Receptor)IBA 01/2022
1	Long Noncoding RNAIBA 01/2022
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 03/2021
1	Ligases (Synthetase)IBA 03/2021
1	TNF Receptor-Associated Factor 6 (TRAF6)IBA 03/2021
1	Transforming Growth Factor beta (TGF-beta)IBA 03/2021
1	TNF Receptor-Associated Factor 4IBA 03/2021
1	UbiquitinIBA 03/2021
1	SalicylatesIBA 05/2020
1	Caspase 3 (Caspase-3)IBA 05/2020
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 05/2020
1	Pharmaceutical PreparationsIBA 05/2020
1	Cyclin D1IBA 05/2020
1	Antisense RNA (Anti-Sense RNA)IBA 01/2019
1	ChromatinIBA 01/2019
1	HymecromoneIBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 08/2014
1	PlasticsIBA 08/2014
1	Hyaluronan ReceptorsIBA 11/2013
1	Metalloproteases (Metalloproteinases)IBA 12/2011
1	Protein Isoforms (Isoforms)IBA 05/2011
1	Cell Surface ReceptorsIBA 11/2010
1	ChemokinesIBA 01/2008
1	Becaplermin (PDGF-BB)FDA Link 10/2007
1	Messenger RNA (mRNA)IBA 06/2007
1	Small Interfering RNA (siRNA)IBA 06/2007
1	Fluorouracil (Carac)FDA LinkGeneric 05/2005

Therapy/Procedure

2	Therapeutics 01/2022 - 05/2011